Enantio- and Diastereoselective Dehydrative 'One-Step' Construction of Spirocarbocycles via a Ru/H

Autor: Yusuke, Suzuki, Namdev, Vatmurge, Shinji, Tanaka, Masato, Kitamura
Rok vydání: 2017
Předmět:
Zdroj: Chemistry, an Asian journal. 12(6)
ISSN: 1861-471X
Popis: Chiral spirocarbocyclic skeletons are ubiquitous in natural products. An intramolecular Tsuji-Trost (T-T) α-allylation of simple cyclic ketones is a reasonable approach to construct chiral spriocarbocyclic motifs; however, it has been a challenging approach despite many excellent intermolecular examples. For the first time, this has been achieved by a Ru/H
Databáze: OpenAIRE