| Autor: |
Murilo S, Meneses, Samanta F Blattes, Rocha, Marcelo R Young, Blood, Alcides, Trentin, Paulo Roberto, Benites Filho, Pedro André, Kowacs, Nelson de Andrade, Oliveira, Cristiane A, Simão, Yumi, Awamura, Maria L A, Vítola |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Arquivos de neuro-psiquiatria. 62(1) |
| ISSN: |
0004-282X |
| Popis: |
Functional magnetic resonance imaging (fMRI) is a technique for detecting minimal changes in brain perfusion and oxygenation secondary to neuronal activation. Its application in the pre-surgical evaluation of epileptic patients with temporal mesial sclerosis is currently being under investigation in several centers. This study aims to describe an activation paradigm for the evaluation of language and memory functions, as an alternative to the worldwide used Wada test, which is an invasive procedure. In order to propose a paradigm adapted to the Portuguese language, we report our experience in determining the dominant cerebral area for language through fMRI with a verbal fluency task. The results of the fMRI from 19 patients studied in Curitiba in a period of approximately two years were studied. Sixteen of them presented with left hemispheric cerebral language dominance. In five patients, results from fMRI and Wada test could be compared and agreed in localization. Our results reinforce the view that fMRI may become an essential tool for medical practice, perhaps for the determination of eloquent areas in the evaluation of candidates for epilepsy surgery. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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