[Esters of naproxen as potential prodrugs for skin penetration. 2. Penetration behavior in excised mice skin]

Autor:	H, Weber, K, Meyer-Trümpener, B C, Lippold
Jazyk:	němčina
Rok vydání:	1994
Předmět:	Male Mice Naproxen Skin Absorption Animals Mice Nude In Vitro Techniques
Zdroj:	Archiv der Pharmazie. 327(11)
ISSN:	0365-6233
Popis:	Penetration of various Naproxen esters was studied in an in vitro model using excised skin of nude mice. Maximal fluxes and permeability coefficients were determined and correlated with physicochemical properties of the substances. The solubilities in octanol and water are of special importance. A model for predicting penetration behaviour was discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::059fdfa00f956b88ff0d6ef9842a2c3a https://pubmed.ncbi.nlm.nih.gov/7840735 Zobrazit plný text záznamu Plný text