| Autor: |
M R, Kuznetsov, N A, Sergeeva, V M, Koshkin, B V, Boldin, S V, Rodionov, A O, Virganskiĭ, I V, Kosykh, O P, Lisenkov, V F, Kuznetsova |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery. 20(1) |
| ISSN: |
1027-6661 |
| Popis: |
Presented in the article are the results of studying antiaggregate activity of acetylsalicylic acid and clopidogrel in a total of 36 patients suffering from various-severity chronic arterial insufficiency of lower limbs on the background of atherosclerosis obliterans. The study was conducted prior to treatment for correct selection of a particular antiplatelet agent. The obtained results showed that clopidogrel was not always more efficient than acetylsalicylic acid, since there is individual sensitivity of each patients to a particular antiplatelet agent. Therefore, an individual approach is necessary to conservative therapy of arterial insufficiency of lower limbs. For some patients it is preferable to administer clopidogrel, for others - acetylsalicylic acid. In a series of cases combined treatment is justified, while some patients having low sensitivity to both acetylsalicylic acid and clopidogrel require careful selection of alternative agents influencing other thrombocyte receptors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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