[Transformation of multiple basaliomas to squamous cell carcinomas in an HIV patient with Gorlin-Goltz syndrome]

Autor:	L U, Wölfer, U, Blume-Peytavi, B, Almond-Roesler, H, Gollnick, C E, Orfanos
Jazyk:	němčina
Rok vydání:	1995
Předmět:	Adult Male Cell Transformation Neoplastic Skin Neoplasms AIDS-Related Opportunistic Infections Biopsy Superinfection HIV Seropositivity Carcinoma Squamous Cell Humans Basal Cell Nevus Syndrome Skin
Zdroj:	Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 46(4)
ISSN:	0017-8470
Popis:	We report on a 32-year-old male patient with Gorlin-Goltz syndrome, who presented with excessive numbers of superinfected basal cell carcinoma. This led us to suspect an underlying HIV infection, which was confirmed by ELISA and Western blotting. Laboratory investigation of the immunological state revealed severe immunosuppression with 267 CD4+ lymphocytes and a CD4/CD8 ratio of 0.3. The histological picture showed multiple basal cell carcinomas, some of them transforming into squamous cell carcinomas. We suspect that the excessive number and the unusual clinical and histological picture of the basal cell carcinomas in this patient were probably influenced by the underlying HIV infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::058477235391ce63cbb964dc0472614c https://pubmed.ncbi.nlm.nih.gov/7790194 Zobrazit plný text záznamu Full text from SpringerLink