| Autor: |
L I, Pavlova, M A, Gorbunov, V N, Borisova, I V, Krasil'nikov, A V, Noskova, B N, Lytsar', S V, Skvortsov, E A, Beliakova, I M, Iakovleva, Iu P, Korovin, A V, Bel'chenko, I A, Titov, M V, Budanov |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Voprosy virusologii. 41(4) |
| ISSN: |
0507-4088 |
| Popis: |
Two yeast recombinant vaccines were compared: the Russian hepatitis B Combiotech vaccine in a dose of 20 mg and the Recombivax-HB vaccine in a dose of 10 mg manufactured in the USA (Merk, Sharp and Dohme Ltd.). Both agents were found safe and low reactogenic. After a course of 3 vaccinations with the Russian vaccine 92.5 to 97.5% subjects vaccinated after the 0-1-2 months and 0-1-6 months protocols had high levels of specific antibodies. In the group vaccinated with the American vaccine, antibodies to HBsAg were found in the sera of 95 to 100% subjects. These results demonstrate high immunological activity of both Russian and American vaccines. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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