| Autor: |
E G, Kolokol'chikova, A A, Pal'tsyn, A I, Shchegolev, A A, Adamian, N V, Chervonskaia, A K, Badikova |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Arkhiv patologii. 66(4) |
| ISSN: |
0004-1955 |
| Popis: |
Common lipomas and destructive ones (intramuscular, infiltrating, necrotizing and destroying surrounding tissues) were studied in 9 patients electron-microscopically and radioautographically. The adequacy of necrotizing processes and regeneration was observed: normal fat tissue-lipoma-destructive lipoma. In the latter besides pronounced destruction of tissue (adipocytes, vessels, muscles at the border with tumour), there was accelerated differentiation of preadipocytes from the cells-precursors (fibroblasts and undifferentiated cells of the vascular wall), hypertrophy of preadipocytes (their size and number of nuclei increase) and their proliferation. The process of malignant transformation in a destructive lipoma may be so much pronounced that DNA synthesis may be observed in the mature lipocyte (this has not been described so far). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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