Design and preparation of proline, tryptophan and poly-l-lysine functionalized magnetic nanoparticles and their radiolabeling with

Autor: Marija, Mirković, Zorana, Milanović, Marko, Perić, Sanja, Vranješ-Đurić, Miloš, Ognjanović, Bratislav, Antić, Milorad, Kuraica, Ivan, Krstić, Martina, Kubovcikova, Iryna, Antal, Radka, Sobotova, Vlasta, Zavisova, Alena, Jurikova, Martin, Fabian, Martina, Koneracka
Rok vydání: 2022
Předmět:
Zdroj: International journal of pharmaceutics. 628
ISSN: 1873-3476
Popis: Surface modification of magnetic nanoparticles with poly-l-lysine, proline, and tryptophan was used to design potential theranostic agents for the application in cancer diagnosis and radionuclide-hyperthermia therapy. Characterization of bare and functionalized magnetic nanoparticles was performed in detail. The transparency of the examined magnetic nanoparticles was measured in the non-alternating magnetic field for a complete and better understanding of hyperthermia. For the first time amino acid-functionalized magnetic nanoparticles were labeled with theranostic radionuclides
Databáze: OpenAIRE