| Autor: |
Robert D, Inman, Daniel O, Clegg, John C, Davis, James B, Whitmore, Alan, Solinger |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
The Journal of rheumatology. 33(8) |
| ISSN: |
0315-162X |
| Popis: |
To determine whether twice-weekly subcutaneous etanercept improves the signs and symptoms of adult patients with early onset ankylosing spondylitis (AS).A retrospective analysis was performed on a subgroup of patients with AS with onset18 years of age from a multicenter, double-blind, placebo-controlled, randomized study of etanercept in the treatment of patients with AS. Twenty patients met criteria and are presented.As early as week four, 5/9 (56%) patients who received etanercept achieved an Assessments in Ankylosing Spondylitis 20% response (ASAS 20) versus only 1/11 (9%) of those who received placebo (p = 0.032). The observed ASAS 20 response continued through week 24, with 6/9 (66%) patients receiving etanercept responding, versus 2/11 of patients receiving placebo (p = 0.025).Etanercept improves signs and symptoms of early onset AS in adult patients for at least 24 weeks. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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