Autor: |
A A, Sereĭskaia, N V, Kostiuchenko, T V, Osadchuk, S B, Serebrianyĭ |
Rok vydání: |
1983 |
Předmět: |
|
Zdroj: |
Ukrainskii biokhimicheskii zhurnal (1. 55(3) |
ISSN: |
0201-8470 |
Popis: |
Partial dithiothreitol-reduction of the disulphide thrombin bonds when denaturating agents are absent lowers significantly enzymic activity of thrombin relative to fibrinogen coagulation. This permits supposing that at least one of the disulphide bridges in a thrombin molecule is necessary for stabilization of the space structure important for a specific hydrolysis of fibrinogen. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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