Therapeutic efficacy and imaging assessment of the HER2-targeting chemotherapy drug Z

Autor:	Jingya, Han, Yan, Zhao, Xinming, Zhao, Tuo, Ma, Tiancheng, Hao, Jiahui, Liu, Zhaoqi, Zhang, Jingmian, Zhang, Jianfang, Wang
Rok vydání:	2019
Předmět:	Tomography Emission-Computed Single-Photon Mice Inbred BALB C Lung Neoplasms Receptor ErbB-2 Recombinant Fusion Proteins Mice Nude Adenocarcinoma of Lung Antineoplastic Agents Apoptosis Cell Cycle Checkpoints Pemetrexed Xenograft Model Antitumor Assays Tumor Burden A549 Cells Animals Humans Female
Zdroj:	Investigational new drugs. 38(4)
ISSN:	1573-0646
Popis:	Chemotherapy has always been the first therapeutic option for patients with advanced non-small cell lung cancer (NSCLC) with untreatable oncogenic mutations. However, chemotherapy has demonstrated limited success and is associated with severe side effects. This research aimed to investigate the antitumor efficacy and cytotoxic safety of the conjugate Z
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::04ae47f284236c8596b5f8d5d9c8e391 https://pubmed.ncbi.nlm.nih.gov/31758360 Zobrazit plný text záznamu Full text from SpringerLink