| Autor: |
Jianlu, Song, Wangwang, Qiu, Xianzhao, Deng, Zhongling, Qiu, Youben, Fan, Zhili, Yang |
| Rok vydání: |
2018 |
| Zdroj: |
American journal of cancer research. 8(9) |
| ISSN: |
2156-6976 |
| Popis: |
Mutation profiles of advanced radioactive iodine (RAI)-refractory differentiated thyroid cancer have revealed the pathogenic roles of the established oncogenic mutations of BRAF and PI3KCA, but the involvement of other genes is presently unknown. In the present study, we performed whole-exome sequencing on 10 tissue samples of metastases of RAI-refractory differentiated thyroid cancers and identified a recurrent hot-spot mutation (c.1924GT) in the |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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