| Autor: |
Yi-Ling, Yan, Jiun-Rung, Guo, Chien-Fu, Liang |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Chemistry, an Asian journal. 12(18) |
| ISSN: |
1861-471X |
| Popis: |
Dysprosium(III) trifluoromethanesulfonate-catalyzed per-O-acetylation and regioselective anomeric de-O-acetylation of carbohydrates can be tuned by adjusting the reaction medium. In this study, the per-O-acetylation of unprotected sugars by using a near-stoichiometric amount of acetic anhydride under solvent-free conditions resulted in the exclusive formation of acetylated saccharides as anomeric mixtures, whereas anomeric de-O-acetylation in methanol resulted in a moderate-to-excellent yield. Reactions with various unprotected monosaccharides or disaccharides followed by a semi-one-pot sequential conversion into the corresponding acetylated glycosyl hemiacetal also resulted in high yields. Furthermore, the obtained hemiacetals could be successfully transformed into trichloroimidates after Dy(OTf) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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