[T-lymphocyte subpopulations in the blood of patients with chronic B-cell lympholeukemia studied using monoclonal antibodies]

Autor: N M, Karminskaia, A G, Merson, N M, Gipsh, O Iu, Udris, L I, Iavorkovskiĭ
Rok vydání: 1986
Předmět:
Zdroj: Eksperimental'naia onkologiia. 8(3)
ISSN: 0204-3564
Popis: The contents of T-lymphocytes and their basic subpopulations (T-helpers and T-suppressors) in peripheral blood of 40 patients with B-cellular chronic lymphatic leukemia was studied (CLL) using monoclonal antibodies. It is shown that an imbalance of T-helpers and T-suppressors is observed in many patients (a ratio of helpers/suppressors less than 1.29 in 24 patients) at the expense of a decrease in the relative content of T-helpers in patients at stage I-III of CLL and an increase in the contents of T-suppressors in patients at stage IV. A correlation is revealed between the ratio of T-helpers and T-suppressors, on the one hand, and the stage of the disease, on the other hand.
Databáze: OpenAIRE