Local anesthetic and antiarrhythmic effect of some imidazolidin-2-one derivatives

Autor: T, Librowski, B, Filipek, R, Czarnecki
Rok vydání: 2000
Předmět:
Zdroj: Acta poloniae pharmaceutica. 57(5)
ISSN: 0001-6837
Popis: A series of the new derivatives of imidazolidin-2-one was investigated in order to determine their local anesthetic and antiarrhythmic activity. All compounds tested showed strong local anesthetic properties and variable effects on adrenaline-, aconitine- and barium chloride- induced arrhythmia. The results suggest that the antiarrhythmic properties of these compounds is related to their local anesthetic properties.
Databáze: OpenAIRE