Value of ascitic fibronectin and cholesterol concentration in the differentiation between malignancy-related and non-malignant ascites

Autor: A, Archimandritis, D, Kapsalas, M, Douvara, M, Tjivras, M, Tsirantonaki, A, Fertakis
Rok vydání: 1996
Předmět:
Zdroj: Annales de medecine interne. 147(3)
ISSN: 0003-410X
Popis: In this prospective study, we tried to evaluate various "humoral tests of malignancy" regarding their efficiency of discriminating between malignancy-related and non-malignant ascites. Fibronectin, total protein, number of cells, LDH, pH, specific gravity and cytology were compared in the ascitic fluid of 51 patients with malignancy-related and 52 patients with non-malignant ascites; patients with tuberculous peritonitis were not included. Ascitic fluid cholesterol was determined in 36 of 51 malignancy-related and in 37 of 52 non-malignant ascites. Cytology and fibronectin were found 100% specific with diagnostic efficiency 87.5% and 94.2% respectively under optimal conditions. Cholesterol was neither sensitive nor specific. It is concluded that fibronectin was a valuable test for malignancy-associated ascites.
Databáze: OpenAIRE