| Autor: |
Gabriela, Guédez, Apiradee, Pothipongsa, Saija, Sirén, Arto, Liljeblad, Saowarath, Jantaro, Aran, Incharoensakdi, Tiina A, Salminen |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
The Biochemical journal. 476(6) |
| ISSN: |
1470-8728 |
| Popis: |
Spermidine is a ubiquitous polyamine synthesized by spermidine synthase (SPDS) from the substrates, putrescine and decarboxylated S-adenosylmethionine (dcAdoMet). SPDS is generally active as homodimer, but higher oligomerization states have been reported in SPDS from thermophiles, which are less specific to putrescine as the aminoacceptor substrate. Several crystal structures of SPDS have been solved with and without bound substrates and/or products as well as inhibitors. Here, we determined the crystal structure of SPDS from the cyanobacterium |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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