| Autor: |
Isaac, Zilinsky, Tamar Brutman, Barazani, Boris, Shenkman, Oren, Weisman, Nimrod, Farber, Uriel, Martinowitz |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Journal of drugs in dermatology : JDD. 15(7) |
| ISSN: |
1545-9616 |
| Popis: |
Between stages of Mohs micrographic surgery, the wound is dressed and the patient waits for the histopathological results.br/To investigate the efficacy of a hemostatic-anesthetic solution-impregnated gauze in decreasing bleeding between Mohs stages.br/Twenty patients were treated with a hemostatic-anesthetic solution composed of tranexamic acid, adrenaline, and lidocaine (TAL), and 20 others were treated with a saline solution for control. At the second Mohs stage, size measurements of the blood stain on a Telfa pad and the defect were recorded. The Rotation Thromboelastometry Method (ROTEM) was used to investigate a possible effect of lidocaine and adrenaline on the clot stability induced by tranexamic acid.br/The ratio of blood stain size to Mohs defect size in the hemostatic anesthetic solution group was 1:1.47, whereas the ratio in the control saline group was 1:3.37 (Plt;.001). Results of the ROTEM test showed that lidocaine and adrenaline did not interfere with the effect of tranexamic acid on clot formation and stability.br/The application of gauze impregnated with tranexamic acid, adrenaline, and lidocaine on a surgical wound may be effective in reducing bleeding between Mohs stages.br /br /emJ Drugs Dermatol./em2016;15(7):851-855. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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