Comparison of Biochemical Parameters and Pathomorphological Changes in Rats Receiving Standard and High-Fat Diets during Modeling of Streptozotocin Diabetes

Autor:	N A, Borozdina, E R, Shaykhutdinova, V A, Palikov, Yu A, Palikova, E N, Kazakova, E S, Sadovnikova, V A, Kazakov, O V, Sintsova, I A, Dyachenko
Rok vydání:	2021
Předmět:	Blood Glucose Animals Humans Rats Wistar Diet High-Fat Streptozocin Diabetes Mellitus Experimental Rats
Zdroj:	Bulletin of experimental biology and medicine. 172(3)
ISSN:	1573-8221
Popis:	The use of a high-fat diet, along with streptozotocin administration, can provide more profound insight into the mechanism of development of complications in diabetes, as well as their treatment. High-fat diet given over 3 weeks before intraperitoneal injection of streptozotocin in a dose of 40 mg/kg promoted the appearance of hyperglycemia in Wistar rats. The biochemical analysis of blood serum revealed increased levels of urea, triglycerides, cholesterol, AST, ALT, and concentration of inorganic phosphates and K
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::03dda08ba87f4f5ccbc1cf10ad1a1a38 https://pubmed.ncbi.nlm.nih.gov/35001304 Zobrazit plný text záznamu Full text from SpringerLink