Nitric Oxide Mobilizes Intracellular Zn

Autor: Chien-Wei, Chen, Luen-Kui, Chen, Tai-Ying, Huang, De-Ming, Yang, Shui-Yu, Liu, Pei-Jiun, Tsai, Tien-Hua, Chen, Heng-Fu, Lin, Chi-Chang, Juan
Rok vydání: 2022
Předmět:
Zdroj: International journal of molecular sciences. 23(10)
ISSN: 1422-0067
Popis: Plasma and tissue zinc ion levels are associated with the development of obesity. Previous studies have suggested that zinc ions may regulate adipocyte metabolism and that nitric oxide (NO) plays a pivotal role in the regulation of adipocyte physiology. Our previous study showed that chronic NO deficiency causes a significant decrease in adipose tissue mass in rats. Studies also suggested that zinc ions play an important modulatory role in regulating NO function. This study aims to explore the role of zinc ions in NO-regulated adipocyte differentiation. We hypothesized that NO could increase intracellular Zn
Databáze: OpenAIRE