Evaluation of the ability of neurobiological, neurodevelopmental and socio-economic variables to predict cognitive outcome in premature infants
| Autor: | A C, Wickremasinghe, T K, Hartman, R G, Voigt, S K, Katusic, A L, Weaver, C E, Colby, W J, Barbaresi |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Neurologic Examination Psychiatric Status Rating Scales Marital Status Developmental Disabilities Infant Newborn Infant Mothers Infant Premature Diseases Prognosis Risk Assessment Socioeconomic Factors Risk Factors Child Preschool Educational Status Humans Female Cognition Disorders Infant Premature Maternal Age |
| Zdroj: | Child: care, health and development. 38(5) |
| ISSN: | 1365-2214 |
| Popis: | When developed in the 1990s, the Neurobiologic Risk Score (NBRS) and Neurodevelopmental Risk Exam (NRE) correlated well with developmental outcomes in premature infants. Given recent advances in neonatology, we assessed their present ability to predict cognitive outcome, alone and combined with socio-economic factors.One hundred and twenty-nine neonates32 weeks gestational age were assessed at 6, 12 and/or 24 months corrected age with the Cognitive Adaptive Test/Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS). Indices of socio-economic status included maternal education and marital status.At 24 months corrected age (n= 67), the NBRS (r=-0.5), maternal education (r= 0.46) and marital status (r= 0.37) correlated with the CAT/CLAMS. These correlations increased when NBRS and maternal education were combined (r= 0.63) and when specific NBRS components (intraventricular haemorrhage, periventricular leukomalacia, seizures) and maternal education were combined (r= 0.66).In the contemporary neonatal intensive care unit, measures used to predict cognitive outcome should incorporate both neurobiological risk factors and socio-economic variables. |
| Databáze: | OpenAIRE |
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