| Autor: |
Vicenç, Torrente-Segarra, Tarek C, Salman-Monte, Íñigo, Rúa-Figueroa, Sabina, Pérez-Vicente, Francisco J, López-Longo, María, Galindo-Izquierdo, Jaime, Calvo-Alén, Alejandro, Olivé-Marqués, Jesus, Ibañez-Ruán, Loreto, Horcada, Ana, Sánchez-Atrio, Carlos, Montilla, Manuel, Rodríguez-Gómez, Elvira, Díez-Álvarez, Victor, Martinez-Taboada, José L, Andreu, Olaia, Fernández-Berrizbeitia, José A, Hernández-Beriain, Marian, Gantes, Blanca, Hernández-Cruz, Ángela, Pecondón-Español, Carlos, Marras, Gema, Bonilla, José M, Pego-Reigosa, Lucia Silva, Fernández |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Clinical and experimental rheumatology. 34(2 Suppl 96) |
| ISSN: |
0392-856X |
| Popis: |
The objective of this study is to determine the prevalence of fibromyalgia (FM) in systemic lupus erythematosus (SLE) patients and to study its relationship to depression and other SLE-related factors.A cross-sectional data analysis from the RELESSER-Transversal Spanish Registry, which includes SLE patients in a national multicentre retrospective charts review, was performed.patients who fulfilled ≥4 ACR 1997 SLE criteria. Main variables were disease duration, depression, sociodemographics, comorbidities, SLE activity symptoms, serological findings, therapies and different disease status indices. Statistical analyses included a descriptive, associative and logistic regression analyses. A literature review was performed.3,591 SLE patients were included, 90.1% women, 34.6 years of age at diagnosis (SD 14.6 years) and 93.1% Caucasians. FM prevalence was 6.2%. SLE patients with disease duration5 years showed more FM than those with duration5 years: 6.9% vs. 4.0%, respectively (p0.05). SLE-FM patients showed higher prevalence of depression compared to non-FM-SLE patients: 53.1% vs. 14.6%, respectively (p0.001). After adjusting by risk factors, the OR (CI) of suffering depression in FM-SLE patients was 6.779 (4.770-9.636), p0.001. The OR of having secondary Sjögren's 2.447 (1.662-3.604), p0.001, photosensitivity 2.184 (1.431-3.334), p0.001, and oral ulcers 1.436 (1.005-2.051), p=0.047.Prevalence of FM in Caucasian SLE patients was high compared to the general population, and was significantly higher in those in later stages of disease. SLE patients with depression showed a strong risk of developing FM. Photosensitivity, oral ulcers and secondary Sjögren's were the only SLE-related factors associated with FM. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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