| Autor: |
P, Westermark, G, Mucchiano, T, Marthin, K H, Johnson, K, Sletten |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
The American journal of pathology. 147(5) |
| ISSN: |
0002-9440 |
| Popis: |
Amyloid deposits in the aortic intima are very common in association with atherosclerosis and aging. In the present study, a major fibril protein purified from amyloid present in human atherosclerotic plaques was shown to be a 69-amino acid N-terminal fragment of apolipoprotein AI. Although senile form of localized apolipoprotein AI-derived amyloidosis has recently been documented in pulmonary vessels of dogs, this is the first example of a localized human amyloid derived from this apolipoprotein. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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