[Increased proteolytic activity of cathepsin D in the skin of rats after administration of various anti-inflammatory drugs]

Autor:	J A, Pałka, Z, Galewska, K, Wróbel
Rok vydání:	1990
Předmět:	Enzyme Activation Male Aspirin Phenylbutazone Indomethacin Anti-Inflammatory Agents Animals Prednisone Collagen Colchicine Cathepsin D Rats Skin
Zdroj:	Przeglad dermatologiczny. 77(5)
ISSN:	0033-2526
Popis:	Cathepsin D activity and type I and III collagens content in the skin of rats treated with some antiinflammatory drugs (acetylsalicylic acid, phenylbutazone, indomethacin, colchicine and prednisone) were evaluated. It was found that investigated drugs evoke increased activity of cathepsin D and decreased collagen content (mainly type I) in this tissue. The correlation between type I collagen content and proteolytic activity was noticed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::02f0aa60d55d8589948a9c26111f527c https://pubmed.ncbi.nlm.nih.gov/2270295 Zobrazit plný text záznamu