| Autor: |
Ting Yue, Qi, Ya Qing, Chen, Jun, Jiang, Yun Kai, Zhu, Xiao Hong, Yao, Jun, Qi |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
International journal of urology : official journal of the Japanese Urological Association. 20(11) |
| ISSN: |
1442-2042 |
| Popis: |
To determine the accuracy of contrast-enhanced transrectal ultrasonography for tumor size measurements of hypoechoic prostate cancer foci located in the peripheral zone.A total of 55 men scheduled for radical prostatectomy, with biopsy-proven cancer in hypoechoic foci located in the peripheral zone, were consecutively enrolled in the present prospective study. Each patient underwent grayscale ultrasound and contrast-enhanced transrectal ultrasonography of the prostate according to a standardized protocol. The maximum tumor diameter on grayscale imaging and contrast-enhanced transrectal ultrasonography was compared with that determined using histopathology.A mean underestimation was documented to be approximately 3.9 mm and 0.6 mm for grayscale and contrast-enhanced transrectal ultrasonography imaging, respectively. Grayscale and contrast-enhanced transrectal ultrasonography imaging underestimated measurements by 76.67% (46 of 60) and 48.33% (29 of 60), whereas overestimated measurements were 20% (12 of 60) and 26.67% (16 of 60), respectively. A strong correlation was observed between contrast-enhanced transrectal ultrasonography and histopathological measurements (r = 0.91, P 0.0001). A weak linear correlation was found between grayscale and histopathological measurements (r = 0.59, P 0.0001). Bland-Altman analysis results were in complete accordance with correlation analysis results. For cases with maximum histopathological tumor diameters ≤10 mm and10 mm, 40% (6 of 15) and 86.67% (39 of 45) were index tumors, respectively (P 0.0001).Contrast-enhanced transrectal ultrasonography is significantly more accurate than conventional grayscale imaging for measuring prostate tumor size, especially for tumors with a diameter10 mm, and it might have a role in preoperative assessment of prostatic index tumor sizes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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