Insulin like growth factor 1 receptor signal transduction to the nucleus

Autor: S A, Rosenzweig, B S, Oemar, N M, Law, U T, Shankavaram, B S, Miller
Rok vydání: 1993
Předmět:
Zdroj: Advances in experimental medicine and biology. 343
ISSN: 0065-2598
Popis: The mechanism by which IGF-1Rs regulate the growth and maintenance of cells in normal and disease states provides an important setting for studies addressing signal transduction events at the nuclear level. With the identification of c-Jun/AP-1 as a nuclear target of IGF-1 action we are provided with a model system for pursuing the molecular mechanisms triggered by IGF-1 action.
Databáze: OpenAIRE