[Preoperative serum levels of the carcinoembryonic antigen (CEA) and prognosis in colorectal cancer]
| Autor: | T, Allende, J L, García Muñiz, F, Vizoso, J M, Del Casar, P, Raigoso, B, Llana, C, Serra, N, Zeidán, M, García-Morán, C, Roiz |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Aged 80 and over Male Adenocarcinoma Middle Aged Prognosis Survival Analysis Disease-Free Survival Carcinoembryonic Antigen Neoplasm Proteins Spain Multivariate Analysis Preoperative Care Biomarkers Tumor Humans Female Life Tables Prospective Studies Colorectal Neoplasms Aged Follow-Up Studies Neoplasm Staging |
| Zdroj: | Revista espanola de medicina nuclear. 20(5) |
| ISSN: | 0212-6982 |
| Popis: | To analyze the prognostic value of the preoperative serum levels of the carcinoembryonic antigen (CEA) in primary colorectal carcinoma.Preoperative serum levels of CEA were analyzed in 275 colorectal cancer patients, who were followed up for a minimum of 5 years, or until death.The percentage of positivities for the preoperative serum levels of CEA (6 ng/ml) was positively and significantly associated with the tumoral stage (A: 10,5%; B: 38,8%; C: 32,2%; y D: 72%; p0,0001). In addition, the elevated serum values of the antigen were significantly associated, in the univariate analysis, with short survival in the overall group of patients (p0,0001). However, the multivariate analysis only showed an independent prognosis value of the CEA in the subgroup of patients with stage C tumors.Preoperative serum levels of CEA may be useful to predict tumoral extension, and also for the prognosis regarding stage C colorectal cancer patients. |
| Databáze: | OpenAIRE |
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