| Autor: |
José María, Mora-Gutiérrez, Nuria, Garcia-Fernandez, M Fernanda, Slon Roblero, Jose A, Páramo, F Javier, Escalada, Danny Jj, Wang, Alberto, Benito, María A, Fernández-Seara |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Journal of magnetic resonance imaging : JMRI. 46(6) |
| ISSN: |
1522-2586 |
| Popis: |
To investigate whether arterial spin labeling (ASL) MRI could detect renal hemodynamic impairment in diabetes mellitus (DM) along different stages of chronic kidney disease (CKD).Three Tesla (3T) ASL-MRI was performed to evaluate renal blood flow (RBF) in 91 subjects (46 healthy volunteers and 45 type 2 diabetic patients). Patients were classified according to their estimated glomerular filtration rate (eGFR) as group I (eGFR 60 mL/min/1.73 mA 28% reduction in cortical RBF was seen in diabetics in comparison with healthy controls (185.79 [54.60] versus 258.83 [37.96] mL/min/100 g, P 3 × 10ASL-MRI is able to quantify early renal perfusion impairment in DM, as well as changes according to different CKD stages of DN. In addition, we demonstrated a correlation of RBF quantified by ASL and GFR estimated by cystatin C.3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2017;46:1810-1817. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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