[Favorable outcome of gemcitabine-induced acute respiratory distress syndrome]

Autor: A, Bonnichon, L, Vedrine, M, Aletti, S, Le Moulec, M, Borne, J, Margery, O, Bauduceau, M, Fayolle, B, Ceccaldi
Jazyk: francouzština
Rok vydání: 2008
Předmět:
Zdroj: Revue de pneumologie clinique. 63(6)
ISSN: 0761-8417
Popis: Gemcitabine is a new important drug used to treat solid tumors including non-small cell lung cancer, pancreatic, bladder and breast cancers. Myelosuppression is the most common adverse effect. Pulmonary toxicity is rare and usually mild and self-limiting with acute dyspnea. Severe pneumonitis and potentially fatal acute respiratory distress syndrome (ARDS) have been described in patients treated for a non-small cell lung cancer. We report a case of gemcitabine-induced ARDS in a 72-year old patient treated with gemcitabine and cisplatin for a bladder cancer without lung metastasis. Administration of high doses of corticosteroids led to a prompt symptomatic improvement.
Databáze: OpenAIRE