Comparative trial of stent-like balloon angioplasty versus coronary stenting for acute myocardial infarction

Autor:	G, Eid-Lidt, R, Villavicencio-Fernández, S, Ponce-De-León-Rosales, J, Gaspar, J, Luna-Guerra, E, Ban-Hayashi, M A, Peña-Duque, M A, Martinez-Rios
Rok vydání:	2001
Předmět:	Male Myocardial Infarction Middle Aged Coronary Vessels Cohort Studies Treatment Outcome Predictive Value of Tests Case-Control Studies Multivariate Analysis Humans Female Stents Coronary Artery Bypass Angioplasty Balloon Follow-Up Studies Retrospective Studies
Zdroj:	Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 53(2)
ISSN:	1522-1946
Popis:	Primary PTCA has been shown to be superior to any thrombolytic regimen and offers higher reperfusion rates and better coronary flow grades. Its limitations include recurrent ischemia (10%-15%), infarct-related artery reocclusion (5%-10%), angiographic restenosis (35%-50%), and need to perform repeat PTCA or CABG at 6-month follow-up (20%). Thus, the current role of coronary stenting for acute myocardial infarction (AMI) is very promising. From December 1995 through January 1997, 335 patients underwent primary angioplasty during the first 12 hr from symptom onset at our institution. We performed a retrospective study comparing the in-hospital and 6-month follow-up outcome of 61 patients who underwent coronary stenting (stent group) against 61 patients with optimal (residual lesion stenosis30%) balloon-only primary angioplasty (stent-like group). Patients were routinely treated with aspirin, and ticlopidine was given only to the stent group. In-hospital major adverse cardiac events (MACE) rate was 11.5% without statistical differences between the groups. Cardiac death rate was similar in both groups (4.9 vs. 6.6%; P = 1.0) and only two (3.3%) patients from the stent group and none from the PTCA group had nonfatal myocardial reinfarction. At 6-month follow-up, the rate of recurrent angina was higher in the stent-like group (30.9 vs. 7.1%; P0.001). Multivariate analysis showed that only stenting of the infarct-related artery was a borderline independent predictor for MACE (OR = 0; 95% CI = 0-1; P = 0.057). Primary stenting for AMI reduces the rate of recurrent angina or symptoms and MACE at 6-month follow-up.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::025f0a8c1522a36c14354b700a826e80 https://pubmed.ncbi.nlm.nih.gov/11387597 Zobrazit plný text záznamu Plný text