| Autor: |
S A, Ivarsson, A, Carlsson, A, Bredberg, J, Alm, S, Aronsson, J, Gustafsson, L, Hagenäs, A, Häger, B, Kriström, C, Marcus, C, Moëll, K O, Nilsson, T, Tuvemo, O, Westphal, K, Albertsson-Wikland, J, Aman |
| Rok vydání: |
1999 |
| Předmět: |
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| Zdroj: |
Acta paediatrica (Oslo, Norway : 1992). 88(9) |
| ISSN: |
0803-5253 |
| Popis: |
This study was undertaken to investigate the prevalence of coeliac disease in children and adolescents with Turner syndrome. Eighty-seven children and adolescents with Turner syndrome were screened for IgA-antiendomysium antibodies (EMA) and IgA-antigliadin antibodies (AGA), 5% (4/87) being found to be EMA-positive, and 15% (13/87) to have AGA levels above normal. Of the 10 patients who were either AGA- or EMA-positive and further investigated with intestinal biopsy, four manifested villous atrophy (i.e. all three of the EMA-positive patients, but only one of the seven AGA-positive patients). The results suggest EMA-positivity to be a good immunological marker for use in screening for coeliac disease, and such screening to be justified in patients with Turner syndrome. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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