| Autor: |
Janev, Fehmi, Alexander J, Davies, Jon, Walters, Timothy, Lavin, Ryan, Keh, Alexander M, Rossor, Tudor, Munteanu, Norman, Delanty, Rhys, Roberts, Dirk, Bäumer, Graham, Lennox, Simon, Rinaldi |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of neurology, neurosurgery, and psychiatry. 92(10) |
| ISSN: |
1468-330X |
| Popis: |
We aimed to define the clinical and serological characteristics of pan-neurofascin antibody-positive patients.We tested serum from patients with suspected immune-mediated neuropathies for antibodies directed against nodal/paranodal protein antigens using a live cell-based assay and solid-phase platform. The clinical and serological characteristics of antibody-positive and seronegative patients were then compared. Sera positive for pan-neurofascin were also tested against live myelinated human stem cell-derived sensory neurons for antibody binding.Eight patients with IgGIgG |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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