Assessment of the diagnostic accuracy of
| Autor: | Ana, Jiménez-Ballvé, María Jesús, Pérez-Castejón, Roberto C, Delgado-Bolton, Cristina, Sánchez-Enrique, Isidre, Vilacosta, David, Vivas, Carmen, Olmos, Manuel E Fuentes, Ferrer, José L, Carreras-Delgado |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Aged 80 and over Male Prosthesis-Related Infections Endocarditis Reproducibility of Results Middle Aged Sensitivity and Specificity Electrodes Implanted Diagnosis Differential Young Adult Fluorodeoxyglucose F18 Heart Valve Prosthesis Positron Emission Tomography Computed Tomography Humans Female Radiopharmaceuticals Aged |
| Zdroj: | European journal of nuclear medicine and molecular imaging. 43(13) |
| ISSN: | 1619-7089 |
| Popis: | The diagnosis of prosthetic valve (PV) infective endocarditis (IE) and infection of cardiac implantable electronic devices (CIEDs) remains challenging. The aim of this study was to assess the usefulness ofWe included 41 patients suspected of having IE by the Duke criteria who underwentWe studied 62 areas with suspicion of IE, 28 areas (45 %) showing definite IE and 34 (55 %) showing possible IE. Visual analysis of only AC PET images showed poor diagnostic accuracy (sensitivity 20 %, specificity 57 %). Visual analysis of both AC PET and NAC PET images showed excellent sensitivity (100 %) and intermediate specificity (73 %), focal uptake being more frequently associated with IE. The accuracy of qualitative analysis of NAC PET images depended on the threshold: the maximum sensitivity, specificity and accuracy achieved were 88 %, 80 %, 84 %, respectively. In the semiquantitative analysis of AC PET images, SUVmax was higher in areas of confirmed IE than in those without IE (∆SUVmax 2.2, p 0.001). When FDG uptake was twice that in the liver, IE was always confirmed, and SUVmax 5.5 was the optimal threshold for IE diagnosis using ROC curve analysis (area under the curve 0.71).The value of |
| Databáze: | OpenAIRE |
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