| Autor: |
E, Hoting, R, Maurach, W, Meigel |
| Jazyk: |
němčina |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
Zeitschrift fur Hautkrankheiten. 57(15) |
| ISSN: |
0301-0481 |
| Popis: |
Retinoids possess regulatory influences on growth and differentiation of epithelial tissues. They induce a population of keratinozytes with normal pattern of differentiation, they have antiproliferative properties, and they show antineoplastic effects by inhibition of malignant transformation of cells in vitro. Also the dermis undergoes distinct alterations under oral administration of retinoids. By stimulating T-lymphocytes and by inhibition of neutrophil migration retinoids seem to develop immunmodulating and antiinflammatory effects. The aromatic retinoid Etretinate is therapeutically used in severe forms of psoriasis and in various genodermatoses with disorders of keratinization as for example ichthyosis, dyskeratosis follicularis Darier, and pityriasis rubra pilaris. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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