[Fetal hemolytic disease in a patient immunized by six antibodies: diagnosis and treatment]

Autor: V, Tantalo, E, Rossi, G A, Gianotti, R, Morotti, G, Zuliani, M, Buscaglia, M, Galligani
Rok vydání: 1990
Předmět:
Zdroj: Annali di ostetricia, ginecologia, medicina perinatale. 111(5)
ISSN: 0300-0087
Popis: A case of severe haemolytic disease of the fetus due to six rare alloantibodies is described. In a pregnant women at 23 weeks gestation after the finding of a positive indirect Coombs test maternal antibodies have been precisely identified and titrated: anti-I: 1/23, anti-c: 1/64, anti-S: 1/16, anti-Fya: 1/128, anti-M: 1/64, anti-Jka: 1/32000. Fetal blood group, free and red blood cell adherent antibodies have been investigated on fetal blood samples obtained by means of cord centesis. A compatible donor has been found. Severe fetal anemia has been corrected by ultrasound guided intrauterine transfusions (one abdominal and two intravascular transfusions) with positive outcome of the pregnancy.
Databáze: OpenAIRE