| Autor: |
S B, Turnipseed, J E, Roybal, A P, Pfenning, S A, Gonzales, J A, Hurlbut, M R, Madson |
| Rok vydání: |
2001 |
| Předmět: |
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| Zdroj: |
Journal of AOAC International. 84(3) |
| ISSN: |
1060-3271 |
| Popis: |
A liquid chromatographic/mass spectrometric (LC/MS) electrospray confirmation method has been developed to confirm 4 ionophores (monensin, lasalocid, salinomycin, and narasin) in a variety of animal feeds using a single quadrupole mass spectrometer. The sodium ions of these compounds are dominant in the electrospray mass spectrum. Using optimized "in-source" collision induced dissociation, characteristic fragment ions seen previously using MS/MS can be observed. The drugs were extracted from the feed matrix using hexane-ethyl acetate and isolated using a silica solid-phase extraction cartridge. These ionophores were confirmed in both medicated feeds and nonmedicated feeds fortified with these drugs at the 1-50 ppm level. In addition, this method was used to confirm residues of monensin in a nonmedicated feed that was collected from a feed mill immediately after the production of a similar feed that was medicated with high levels of monensin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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