Changes in the antioxidant system and level of proinflammatory cytokin IL-1beta in the blood patients of sufferi

Autor: N V, Fartushok, O P, Khavrona, Yu M, Fedevych, O Ya, Sklyarov
Rok vydání: 2012
Předmět:
Zdroj: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 58(1)
ISSN: 2522-9028
Popis: Diabetes mellitus type 1 provokes the development of the oxidative stress, accompanied by the increased level of TBA-active products, activation of NO-synthases and increased production of nitric oxide. Activation of glutathione reductase, decrease of the glutathione peroxidase and superoxide dismutases activity was observed. This shows a specific disturbance in the functioning of the antioxidant defense system and the augmentation in the concentration of one of the major first line reacting cytokin (IL-1beta).
Databáze: OpenAIRE