Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report

Autor: Mami, Ikram, Ghzel, Emna, Abida, Rym, Hlaoui, Fadwa, Jebali, Hela, Rais, Lamia, Beji, Soumaya, Hamida, Fethi Ben, Fatma, Lilia Ben, Zouaghi, Karim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Pan African Medical Journal; Vol. 39 No. 1 (2021)
The Pan African Medical Journal
ISSN: 1937-8688
Popis: Anti-glomerular basement membrane (anti-GBM) disease was usually described as a small vessel vasculitis presenting with acute kidney injury, haematuria and non-nephrotic proteinuria. We report a case of anti-GBM disease revealed by an intense nephrotic syndrome. The urinary protein level was 12g/day. Renal biopsy only showed crescent glomerulonephritis with linear staining of IgG in direct immunofluorescence without other glomerulonephritis. Immunoglobulin G (IgG) anti-GBM antibody titer was elevated.
Databáze: OpenAIRE