Reversible Calcineurin Inhibitor-associated Sensorimotor Polyneuropathy in a Lung Transplant Recipient: A Case Report

Autor: Antychin, T., Zarowski, J.A., Verplancke, V., Hendriks, Jeroen, Yogeswaran, Suresh Krishnan, Lauwers, Patrick, Lamote, Kevin, Kwakkel-van Erp, Johanna
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Int J Organ Transplant Med
International Journal of Organ Transplantation Medicine
ISSN: 2008-6482
Popis: Calcineurin inhibitors (CNIs) are regarded as a corner stone in immunosuppressive therapy after solid organ transplantation. However, neurotoxicity is a common side effect of CNIs, resulting in a wide range of neurological symptoms such as headache, tremor and seizures. In this case report, we describe a patient who developed severe motor and sensory neuron dysfunction related to CNIs after bilateral lung transplantation, which resolved after halting CNI and switching to a mammalian Target of Rapamycin-inhibitor.
Databáze: OpenAIRE