Novel Labeling Schemes for Single-Molecule Nanoscopy

Autor: Schoen, Ingmar, Kaplan, Charlotte, Platonova, Evgenia, Vogel, Viola, Ewers, Helge, Ries, Jonas
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Popis: Single molecule localization-based superresolution microscopy methods, such as PALM or STORM, have been breakthrough techniques of the last years. Until now however, they require special fluorescent proteins to be cloned or high-affinity antibodies to be generated for specific labeling. On the other hand, many laboratories will have most of their constructs in GFP form and entire genomes are available as functional GFP-fusion proteins.
Databáze: OpenAIRE