Severe nonimmune hydrops fetalis and congenital corneal opacification secondary to human parvovirus B19 infection. A case report
| Autor: | Plachouras, N., Stefanidis, K., Andronikou, S., Lolis, D. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
Adult
Corneal Opacity/*congenital/diagnosis/*virology Parvovirus B19 Human/immunology Fetal Blood/chemistry Fetal Diseases/diagnosis/immunology/therapy/*virology Ultrasonography Prenatal Pleural Effusion/*congenital/diagnosis/*virology Hydrops Fetalis/diagnosis/therapy/*virology Parvoviridae Infections/complications/diagnosis/immunology/therapy/*virology Ascites/*congenital/diagnosis/*virology Antibodies Viral/analysis Humans Blood Transfusion Female |
| Popis: | BACKGROUND: In parvovirus infections in animals, congenital anomalies are seen, but the teratogenic potential in humans seems fairly low. CASE: A fetus with hydrops, ascites and pleural effusion was seen at a prenatal ultrasound examination. Fetal cordocentesis was performed, and fetal blood was positive for parvovirus antibodies. Intravascular fetal blood transfusion was given at 21 and 23 weeks of gestation. At 39 weeks labor started spontaneously, and a 2,960-g, female infant was delivered. The newborn had bilateral opacification of the cornea. CONCLUSION: In this case a combination of fetal parvovirus B19 infection and congenital corneal opacification was seen. This case also demonstrates that blood transfusions in hydropic fetuses may reverse the hydrops and prevent intrauterine death. J Reprod Med |
| Databáze: | OpenAIRE |
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