| Autor: |
Siamopoulos, K. C., Gouva, C., Katopodis, K. P., Tzallas, C., Nikolopoulos, P., Papavasiliou, E. C., Tselepis, A. D. |
| Jazyk: |
angličtina |
| Rok vydání: |
2006 |
| Předmět: |
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| Popis: |
Background. Among lipid abnormalities observed in patients with chronic kidney disease (CKD) is a significant decrease in serum high-density lipoprotein cholesterol (HDL-C) levels. In a previously published randomized control trial, we showed that early erythropoietin (EPO) administration in a predialysis population slowed the progression of CKD. In the present nested substudy, we examine whether EPO has an influence on serum HDL-C levels in comparison to other lipid parameters in this population. Methods: Eighty-eight patients with CKD stages 3 and 4 were enrolled in the study. Forty-five patients (group 1) were treated with EPO (50 U/kg/wk), targeting to increase hemoglobin levels to 13 g/dL or greater ( >= 130 g/L). The other patients (group 2) remained without treatment until hemoglobin levels decreased to less than 9 g/dL ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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