| Autor: |
Katsanos, K. H., Tatsioni, A., Natsi, D., Sigounas, D., Christodoulou, D. K., Tsianos, E. V. |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Popis: |
AIM OF THE STUDY: To describe our 15-year experience on the patients' response and safety to the use of EPO in IBD patients with refractory anemia. PATIENTS-METHODS: Single center retrospective chart analysis of all IBD patients receiving EPO for the period 1994-2009. Patients with resistant anemia not responding to I.V. iron therapy were enrolled. Concommitant medication, medical and laboratory data on short and long-term patients' responses and safety were recorded. RESULTS: In total 820 IBD files were reviewed and among 78 patients treated with I.V. iron we identified 26 patients who received EPO in concordance to our inclusion criteria. Azathioprine or methotrexate was administered in 17 patients and 7 patients received concomitant Infliximab. After EPO, 22/26 patients (84.6%) responded and peripheral blood parameters were significantly improved and blood transfusions were significantly decreased (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
