Popis: |
The radioprotective efficacy of grape seed extract (GSE) and vitamin E against whole body X-radiation was studied in Albino Wistar rats. Three groups of rats were investigated: control group (CG) intraperitoneal (i.p.) physiological serum 1 ml/day (n = 10), i.p., vitamin E group (VG) 50 mg/kg/day (n = 10), and i.p. grape seed extract group 50mg/kg/day (n=10). Four weeks later, 6 Gy radiation dose was given to rats. The blood samples were taken 24 hours later after irradiation and Lymphocyte, malondialdehyde (MDA), reduced glutathione (GSH), nitrate, nitrite, reduced ascorbic acid, retinol, (β-caratone and ceruloplasmin concentrations were analyzed. The levels of GSH (p |