| Autor: |
Lambregts, M. Mc, Hendriks, B. Jc, Sijbom, M., Sigaloff, K., Nieuwhof, C., de Boer, M. Gj |
| Jazyk: |
Dutch; Flemish |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Lambregts, M M, Hendriks, B J, Sijbom, M, Sigaloff, K, Nieuwhof, C & de Boer, M G 2020, ' Kruisallergie van penicillines met cefalosporines ', Nederlands Tijdschrift voor Geneeskunde, vol. 164 . |
| Popis: |
Penicillin allergy is commonly reported and often influences selection of antimicrobial treatment. Due to concerns about cross-allergic reactions, other beta-lactams - particularly cephalosporins - may also be avoided. This too often results in less effective treatment, more side effects and overconsumption of reserve antimicrobial agents. Most patients (> 90%) with a penicillin allergy label are not truly allergic, i.e., they do not have an 'immediate type' (IgE-mediated) allergy when tested. Based on current data, even in patients with a true penicillin allergy, the risk of severe cross-allergic reactions to cephalosporins is very low. Clinicians tend to overestimate this risk: this dilemma can be resolved with a systematic appraisal of risk probabilities. The limited risk of a true penicillin allergy being present and the subsequent low risk of a cross-allergic reaction to cephalosporins generally outweighs the disadvantages of selecting an alternative (non-beta-lactam) antimicrobial regimen. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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