Therapy-related refractory anemia with ringed sideroblasts in chronic lymphocytic leukemia: involvement of 3q21 region

Autor: Sucak, GT, Yagci, M, Haznedar, R, Ogur, G
Jazyk: angličtina
Rok vydání: 2001
Předmět:
Popis: Therapy-related myelodysplastic syndrome/acute myelogenous leukemia (t-MDS/AML) is extremely rare in chronic lymphocytic leukemia (CLL) despite extensive use of alkylating agents. We present a case of heavily treated CLL with resultant therapy-related refractory anemia with ringed sideroblasts (RARS). A complex cytogenetic abnormality including involvement of 3q21 was detected and to our knowledge, is the first report of a RARS case with a 3q21 abnormality. (C) 2001 Elsevier Science Inc. All rights reserved.
Databáze: OpenAIRE