| Autor: |
Ulu, Z.O., Ulu, S., Dogan, S., Tuna, B.G., Ozgenturk, N.O. |
| Přispěvatelé: |
Ulu, Z.O., Ulu, S., Dogan, S., Tuna, B.G., Ozgenturk, N.O., Yeditepe Üniversitesi |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Popis: |
Calorie restriction (CR), which is a factor that expands lifespan and an important player in immune response, is an effective protective method against cancer development. Thymus, which plays a critical role in the development of the immune system, reacts to nutrition deficiency quickly. RNA-seq-based transcriptome sequencing was performed to thymus tissues of MMTV-TGF-? mice subjected to ad libitum (AL), chronic calorie restriction (CCR), and intermittent calorie restriction (ICR) diets in this study. Three cDNA libraries were sequenced using Illumina HiSeq™ 4000 to produce 100 base pair-end reads. On average, 105 million clean reads were mapped and in total 6091 significantly differentially expressed genes (DEGs) were identified (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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