| Autor: |
Küçük, Ö., Bic?r, S., Giray, T., Co¸¨l, D., Erdag, G.Ç., Gürol, Y., Vitrinel, A. |
| Přispěvatelé: |
Küçük, Ö., Bic?r, S., Giray, T., Co¸¨l, D., Erdag, G.Ç., Gürol, Y., Vitrinel, A., Yeditepe Üniversitesi |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Popis: |
Objective: To evaluate the utility of rapid antigen detection testing (RADT) for the diagnosis of group A beta-hemolytic streptococcal tonsillopharyngitis in children, and to detect the sensitivity and specificity of rapid antigen detection of group A beta-hemolytic streptococci from throat specimen compared with throat culture. Methods: Rapid antigen detection and throat culture results for group A beta-hemolytic streptococci from outpatients attending university hospital between 1st January 2011 and 31st of December 2011 were evaluated retrospectively. The antigen test negative-throat culture positive patients were investigated for streptococcal carriage. For this purpose, the throat culture results taken from these patients were reviewed after treatment. Results: Eighthundred and ninetytwo children were included in the study with a mean age of 5.34 y. There were 639 and 253 children in two groups with age of 0-6 and 7-17 y, RADT sensitivity and specificity were found to be 59.5% and 97.2%, respectively. The positive predictive value was 87.1%, whereas negative predictive value was 88.4%. After treatment of 74 patients with throat culture positive and antigen test negative. Group A beta-hemolytic streptococci were isolated in 12 of them (16.2%) and accepted as a carrier. Conclusions: The low sensitivity of the RADT may be related to streptococcal carriage in some patients. The throat culture should be repeated after treatment to detect streptococcal carriage. © Dr. K C Chaudhuri Foundation 2013. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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