Food protein induced proctocolitis in neonates and infants: Clinical, endoscopic, histopathological findings and treatment

Autor: Gülcan, E.M., Saf, C., Çomunoglu, N., Sözübir, S., Cengizlier, R., Vitrinel, A.
Přispěvatelé: Gülcan, E.M., Saf, C., Çomunoglu, N., Sözübir, S., Cengizlier, R., Vitrinel, A., Yeditepe Üniversitesi
Jazyk: turečtina
Rok vydání: 2009
Předmět:
Popis: Aim: Allergic proctocolitis is a major cause of rectal bleeding in infants, but it's clinical features and laboratory results are often nonspecific. The aim of this study was to present clinical and diagnostic features in infants with food protein-induced proctocolitis. Material and Method: Data of 18 infants with food protein-induced proctocolitis, who had received colonoscopy and biopsy, were analyzed considering clinical and laboratory findings, endoscopical and histopathological features, and response to treatment. Results: The mean age at the onset of symptoms was 8.9 weeks (range 4-20 weeks). Infants were admitted with apparent rectal bleeding (11%) or blood streaked/dappled stool (89%). Feeding at onset of bleeding was exclusively breastfed (83%) or formula fed (17%). Laboratory findings were nonspecific. Endoscopic abnormalities were observed in all patients, and in 67%lenfonodular hyperplasias and in 50% erosions were determined. Histopathological findings were eosinophils in lamina propria of 20-60 cells/10 high power fields in 78% and of 60 cells/10 high power fields.
Databáze: OpenAIRE