| Autor: |
Kural, A., Neijmann, Ş.T., Toker, A., Doğan, H., Sever, N., Sarıkaya, S. |
| Přispěvatelé: |
Kural, A., Neijmann, Ş.T., Toker, A., Doğan, H., Sever, N., Sarıkaya, S., Yeditepe Üniversitesi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
BACKGROUND: Although traumatic brain injury (TBI) is an important problem, there has been no widespread utilization of neuro-biomarkers to aid the diagnosis of TBI. This study was conducted to evaluate serum S100B and prion protein (PrPC) levels in rats with TBI. METHODS: In this study, 15 albino rats were categorized into three groups as follows: sham-operated (1), control (6) and trauma (8) groups. The TBI model was based on the modified free falling model. S100B, PrPC levels were measured using ELISA. Brain specimens were obtained for the pathological examination. RESULTS: Serum S100B and PrPC levels were found to increase in T group at both 2h and 24h after trauma (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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